Estrés y sobreproducción de mucina responsables del asma

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En México, 7 por ciento de la población vive con asma y 6 mil personas mueren en nuestro país a causa de esta enfermedad

 
En el mundo existen aproximadamente 300 millones de personas que viven con asma. En México, alrededor del siete por ciento de los mexicanos tiene esta enfermedad y seis mil personas mueren en el país a causa de esta enfermedad, según datos del Instituto Nacional de Enfermedades Respiratorias (INER).
De acuerdo con la especialista del INER, María del Carmen Cano Salas, 80 por ciento de adultos que padece esta enfermedad presenta síntomas desde los primeros cinco años de vida , cuando el padecimiento puede detectarse desde el primer año de vida, mediante el estudio llamado espirometría.
Ante esta problemática, investigadores del Houston Methodist Hospital desarrollan una investigación para encontrar la manera reducir la producción excesiva de mucina durante un episodio de asma, con lo que los ductos de aire quedarán libres y los pacientes no tendrán esa sensación de asfixia.
Los especialistas explican que la obstrucción de vías respiratorias durante un ataque de asma, es debido a la sobreproducción de una proteína altamente pegajosa secretada por las mucosas de las vías respiratorias, llamada mucina, que obstruye los conductos pequeños y evita que el aire entre y salga a través de ellos.
“Dentro de las células epiteliales de los bronquios existe un tipo muy importante de células que se llaman células productoras de mucina, las cuales son vitales para mantener la superficie hidratada y saludable. Estas secretan mucina para proteger las vías respiratorias, pero la producción excesiva puede ser perjudicial”, enfatizó el doctor Xian Li, director de la investigación.
El estudio de los especialistas parecer ser prometedor para el desarrollo de una nueva clase de medicamentos que sería radicalmente diferente de los esteroides que se usan actualmente para tratar el asma, enfermedad no curable, pero sí controlable. Los expertos esperan que este hallazgo pueda ser el inicio de una ventana de esperanza para mejorar la calidad de vida de los pacientes con asma. (
Agencia ID)

Source: internacional

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